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Product Name | ABCC8 ELISA Kit |
Description | Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of ABCC8 in human tissue homogenates, cell lysates. Target Information: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed\, however, the transcript variants have not been fully described. [provided by RefSeq, Jul 2008]. |
Size | 96 tests |
Concentration | n/a |
Applications | ELISA |
Other Names | ABC36|HHF1|HI|HRINS|MRP8|PHHI|SUR|SUR1|SUR1delta2|TNDM2|ATP-binding cassette sub-family C member 8|ATP-binding cassette transporter sub-family C member 8|sulfonylurea receptor (hyperinsulinemia)|sulfonylurea receptor 1|ATP binding cassette subfamily C member 8|ABCC8|ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8|ATP-binding cassette|sub-family C (CFTR\/MRP)|member 8|sulphonylurea receptor 1|sub-family C|D930031B21Rik|sulfonylurea receptor|sulfonylurea receptor subunit 1 |
Gene, Accession, CAS # | Gene ID: 6833 |
Catalog # | ABIN6953985 |
Price | $773 |
Order / More Info | ABCC8 ELISA Kit from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |