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Product Name | Aspartate beta Hydroxylase ELISA Kit |
Description | Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of ASPH in human serum, plasma, tissue homogenates, cell lysates, cell culture supernates. Target Information: This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis. [provided by RefSeq, Sep 2009]. |
Size | 96 tests |
Concentration | n/a |
Applications | ELISA |
Other Names | AAH|BAH|CASQ2BP1|HAAH|JCTN|junctin|A beta H-J-J|ASP beta-hydroxylase|aspartyl\/asparaginyl beta-hydroxylase|aspartyl\/asparaginyl-beta-hydroxylase|cardiac junctin|humbug|junctate|peptide-aspartate beta-dioxygenase|aspartate beta-hydroxylase|ASPH|Aspartate beta Hydroxylase|2310005F16Rik|3110001L23Rik|AI848629|AW261690|AW561901|C79816|cI-37|aspartyl beta-hydroxylase|calsequestrin-binding protein|jumbug|aspartate-beta-hydroxylase|MGC107896|aspartate beta-hydroxylase L homeolog|asph.L|cb971|fb69e10|fc06d04|fc95a08|wu:fb69e10|wu:fc06d04|wu:fc95a08|junctional sarcoplasmic reticulum protein |
Gene, Accession, CAS # | Gene ID: 444 |
Catalog # | ABIN6953949 |
Price | $773 |
Order / More Info | Aspartate beta Hydroxylase ELISA Kit from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |