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Product Name | PB 28 (hydrochloride) |
Description | A σ receptor ligand with anticancer and antiviral activites; binds to σ1 and σ2 receptors (Kis = 13 and 0.28 nM, respectively, in MCF-7 cell membranes); selective for σ1 and σ2 receptors over hERG channels (Ki = 1,000 nM); inhibits growth of MCF-7 and multidrug-resistant MCF-7/adr cells (IC50s = 25 and 15 nM, respectively); decreases basal P-gp levels in the same cells; reduces SARS-CoV-2 infectivity in Vero E6 cells (IC90 = 278 nM) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 172906-90-0 PB28 σ 1 2 MCF7 anti cancer viral multi drug h ERG Pgp E 6 hydroxy chloroquine SARSCoV2 covid 19 corona virus |
Gene, Accession, CAS # | CAS: 172907-03-8 |
Catalog # | 31742-10 |
Price | $139.00 |
Order / More Info | PB 28 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |