Sphingosine Kinase 1 Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY
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| Product Name | Sphingosine Kinase 1 Inhibitor Screening Assay Kit |
| Description | Cayman's SPHK1 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human SPHK1, an enzyme implicated in the control of diverse biological functions including cell proliferation, survival and differentiation, cell migration and tissue invasion, and angiogenesis and vascular integrity. The assay uses an SPHK-specific fluorogenic substrate, NBD-sphingosine. SPHK1 phosphorylates this substrate, generating a shift in its spectral properties, which can be easily quantified using a fluorescence plate reader at excitation and emission wavelengths of 550 and 584 nm, respectively. The potent and reversible SPHK1 inhibitor PF-543 is included as a positive control and inhibits SPHK1 with an IC50 value of approximately 220 nM. |
| Size | 96 Well |
| Concentration | n/a |
| Applications | Fluorescence |
| Other Names | SK1|SPHK1 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 701740-96WELLS |
| Price | $458.00 |
| Order / More Info | Sphingosine Kinase 1 Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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