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Product Name | Amitriptyline (hydrochloride) |
Description | A tricyclic antidepressant; inhibits 5-HT uptake by isolated human platelets by 39 and 68% at 1 and 4 µg/ml, respectively; inhibits norepinephrine uptake by rat brain by 77% at 10 mg/kg; an antagonist of 5-HT2A receptors (Ki =20 nM), as well as histamine H1, muscarinic acetylcholine, and α1-adrenergic receptors (Kis = 1.1, 18, and 27 nM, respectively); prevents acid sphingomyelinase activation and subsequent ceramide release induced by pp-VSV-SARS-CoV-2 infection in Vero cells at 5-25 µM |
Size | 5 g |
Concentration | n/a |
Applications | n/a |
Other Names | NIH 10794|Ro 4-1575 |
Gene, Accession, CAS # | CAS: 549-18-8 |
Catalog # | 15881-5 |
Price | $32.00 |
Order / More Info | Amitriptyline (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |