K777 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for K777 products.
| Edit | |
|---|---|
| Product Name | K777 |
| Description | A cysteine protease inhibitor; inhibits human cathepsin S and cathepsin L (Kis = 0.002 and 0.05 µM) and is selective for these proteases over human cathepsin K, -B, and -C (Kis = 0.4, 3, >100 µM, respectively), as well as SARS-CoV-2 PLpro and Mpro (Kis = >100 µM for both); prevents cleavage of the spike protein S1 subunit in vitro and reduces the cytopathic effect of SARS-CoV-2 in infected Vero E6, HeLa/ACE2, and A549/ACE2 cells (EC50s = T. b. brucei trypanosomes (IC50 = 0.1 µM) and reduces myocardial damage in a canine model of T. cruzi infection at 50 mg/kg twice per day; inhibits CCL17 binding to, and CCL17-induced chemotaxis of, HuT 78 cells (IC50s = 0.057 and 0.0089 µM, respectively) |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ?APC-3316|CRA-3316|K11777|MePip-Phe-hPhe-VSφ |
| Gene, Accession, CAS # | CAS: 233277-99-1 |
| Catalog # | 19114-10 |
| Price | $380.00 |
| Order / More Info | K777 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY
Return to Products