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Product Name | Abaloparatide (acetate) |
Description | A synthetic derivative of PTHrP (1-34) and an agonist of PTH1R; selectively binds to the RG over the R0 conformation of PTHrP; induces cAMP signaling more transiently than PTH (1-34), PTHrP (1-36), or LA-PTH (EC50s = 0.08, 0.44, 0.46, and 0.21 nM, respectively); increases areal bone mineral density in the lumbar spine, total femur, and femur diaphysis in ovariectomized osteopenic rats at 5 and 20 µg/kg per day for six weeks; increases the incidence of focal osteoblast hyperplasia, benign osteoblastoma, and osteosarcoma in rats in a time- and dose-dependent manner at ≥10 µg/kg per day for up to two years |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BA 058|BIM 44058 |
Gene, Accession, CAS # | n/a |
Catalog # | 28816-5 |
Price | $116.00 |
Order / More Info | Abaloparatide (acetate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |