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Product Name | PAD2 Inhibitor Screening Assay Kit (AMC) |
Description | PAD2 is a guanidino-modifying enzyme that catalyzes the conversion of specific arginine residues to citrulline in a calcium-dependent manner. This enzyme has been implicated in several diseases, including rheumatoid arthritis (RA), retinal degeneration, and certain cancers. PAD2 has been shown to modify vimentin, fibrinogen, and β/γ-actin. Extracellular levels of PAD2 are increased in the lungs of smokers, providing a link between smoking as a risk factor for RA and anti-citrullinated protein antibodies among RA patients. Cayman's PAD2 Inhibitor Screening Assay Kit (AMC) provides a convenient method for screening human PAD2 inhibitors. |
Size | 96 Well |
Concentration | n/a |
Applications | Fluorescence, High-Throughput Screening |
Other Names | PAD-H19|PADI2|Peptidylarginine Deiminase 2|Protein Arginine Deiminase 2 |
Gene, Accession, CAS # | n/a |
Catalog # | 701390-96WELLS |
Price | $493.00 |
Order / More Info | PAD2 Inhibitor Screening Assay Kit (AMC) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |