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Product Name | Emetine (hydrochloride hydrate) |
Description | An alkaloid with diverse biological activities; active against several strains of E. histolytica amoebae (IC50s = 0.73-10.22 µg/ml); inhibits NF-κB signaling induced by TNF-α or IL-1β (IC50s = 2 and 4.2 µM, respectively, in a cell-based β-lactamase reporter assay); increases caspase-3/7 activity in ME180 cells (EC50 = 1.1 µM); cytotoxic to HeLa cells; reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s = 0.46 and 0.5 µM, respectively); induces emesis in ferrets at 5 mg/kg, an effect that can be prevented by ondansetron |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 483-18-1 316-42-7 NSC 33669 NSC33669 Cephaeline Emetin Entamoeba NFκB TNFα IL1β ME-180 HT-3 5HT 5HT3 anti-viral SARS-CoV-2 SARSCoV2 covid-19 covid19 coronavirus corona virus |
Gene, Accession, CAS # | CAS: 7083-71-8 |
Catalog # | 21048-50 |
Price | $266.00 |
Order / More Info | Emetine (hydrochloride hydrate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |