Nebivolol (hydrochloride) from CAYMAN CHEMICAL COMPANY
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| Product Name | Nebivolol (hydrochloride) |
| Description | A β1-AR antagonist (IC50 = 7.41 nM); selective for β1- over β2-ARs (IC50 = 251 nM), as well as 5-HT1A and 5-HT2, α1- and α2-adrenergic, histamine H1, and dopamine D2 receptors (IC50s = 27.5, 2,239, 3,162, >10,000, 5,623, and 10,000 nM, respectively); induces vasodilation in isolated mouse renal arteries (EC50 = 11.36 µM) and decreases isoproterenol-induced contraction of isolated human left ventricular trabeculae (IC50 = 7 µM); inhibits proliferation of primary HCASMCs in the presence and absence of growth factors (IC50s = 6.1, 6.8, 6.4, and 7.7 µM for HCASMCs grown in media containing no growth factor, PDGF-BB, basic FGF, and TGF-β1, respectively); an inhibitor of the SARS-CoV-2 Mpro (IC50 = 60.2 µg/ml); inhibits SARS-CoV-2 pathogenicity in vitro (IC50 = 0.03 µg/ml),, |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 118457-14-0 R067555 Nebicard Nebilet Nodon β1AR β2AR 5HT 5HT1A 5HT2 TGFβ1 R-067555 NO platelet-derived transforming fibroblast PDGF-BB |
| Gene, Accession, CAS # | CAS: 152520-56-4 |
| Catalog # | 23660-10 |
| Price | $68.00 |
| Order / More Info | Nebivolol (hydrochloride) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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