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Product Name | Mitoxantrone (hydrochloride) |
Description | An inhibitor of DNA topoisomerase IIα and HIV-1 integrase (IC50s = 5.3 and 3.8 µM, respectively); intercalates DNA in a cell-free assay at 2 µM; inhibits DNA synthesis and induces DNA-protein crosslinks in vitro; inhibits the growth of K562 and K562-derived etoposide-resistant K/VP.5 cells (IC50s = 0.42 and 1.68 µM, respectively); inhibits HIV-1 integrase (IC50 = 3.8 µM); inhibits the membrane fusion of a mixed population of HEK293T cells expressing either ACE2 or the extracellular domain SARS-CoV-2 spike glycoprotein; inhibits the entry of SARS-CoV-2 into Vero E6 cells at 0.2 µM |
Size | 500 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NCI 301739|NSC 301739 |
Gene, Accession, CAS # | CAS: 70476-82-3 |
Catalog # | 14842-500 |
Price | $456.00 |
Order / More Info | Mitoxantrone (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |