Derenofylline from CAYMAN CHEMICAL COMPANY

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Product NameDerenofylline
DescriptionAn adenosine A1 receptor antagonist (Ki = 1 nM); selective for adenosine A1 over A2A, A2B, and A3 receptors (Kis = 398, 3,981, and 200 nM, respectively); decreases adenosine A1 receptor-mediated adenosine-induced bradycardia in rats (ED50 = 0.49 mg/kg) but reduces A2 receptor-mediated adenosine-induced hypotension by only 44.6% at an intravenous dose of 5 mg/kg; prevents increases in heart levels of collagen I and III in nephrectomized rats at 10 mg/kg per day; reduces relative plaque counts in a Zika virus plaque-forming assay in A549 cells (IC50 = 58.6 nM) in an adenosine A1 receptor-independent manner
Size5 mg
Concentrationn/a
Applicationsn/a
Other NamesSLV 320
Gene, Accession, CAS #CAS: 251945-92-3
Catalog #27666-5
Price$92.00
Order / More InfoDerenofylline from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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