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Product Name | Homoharringtonine |
Description | An alkaloid; inhibits diphenylalanine formation by rabbit reticulocyte and human placental ribosomes in cell-free assays; binds to human 80S ribosomes (Kd = 38.8 nM); reduces the viral load in vitro and in vivo and prevents severe symptoms in porcine and chicken models of PEDV and NDV, respectively; reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s = 2.55 and 2.14 µM, respectively); inhibits the growth of P. falciparum in cultured in human erythrocytes (IC50 = 4 nM); inhibits the proliferation of Jurkat acute T cell leukemia (IC50 = 9 nM) and K562 CML cells (IC50 = 408 µg/ml); decreases the number of peripheral leukemia stem cells and increases survival in CML and B-ALL mouse models , |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NSC 141633|Omacetaxine Mepesuccinate |
Gene, Accession, CAS # | CAS: 26833-87-4 |
Catalog # | 14631-1 |
Price | $36.00 |
Order / More Info | Homoharringtonine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |