DUN41875 from CAYMAN CHEMICAL COMPANY
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| Product Name | DUN41875 |
| Description | A stearoyl-CoA desaturase 1 inhibitor (IC50 = 11.8 nM for the rat enzyme); increases tetramerization of soluble α-synuclein and reduces mutant α-synuclein incorporation into tetramers in BE(2)-M17 cells expressing the 3K mutant α-synuclein at 0.01, 0.1, and 1 µM; reduces the plasma ratio of oleic acid to stearic acid in rats fed a low essential fatty acid diet at 10 or 30 mg/kg; reduces the time to turn and the number of falls in the pole test, increases time to fall from the rotarod, and improves endurance in the hanging wire test in the 3K-3798 transgenic mouse model of Parkinson's disease when administered in the drinking water at 1.9% (v/v); reduces cortex somatic aggregates of phosphorylated α-synuclein and cortex levels of LAMP-1 in the brains from the same mice |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | SCD1 Inhibitor|Stearoyl-CoA Desaturase 1 Inhibitor|Stearoyl-Coenzyme A Desaturase 1 Inhibitor |
| Gene, Accession, CAS # | CAS: 1295541-87-5 |
| Catalog # | 37151-25 |
| Price | $89.00 |
| Order / More Info | DUN41875 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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