Carvedilol from CAYMAN CHEMICAL COMPANY
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| Product Name | Carvedilol |
| Description | A β-adrenergic receptor antagonist (Kds = 1.78, 0.4, and 5.01 nM for β1-, β2-, and β3-ARs, respectively); selectively binds to α1- over α2-ARs (Kis = 0.81 and 3,400 nM, respectively); reverses increases in heart rate induced by isoproterenol in isolated guinea pig atria (Kb = 0.8 nM); prevents epinephrine-induced premature ventricular beats in a rat model of arrhythmia (ED50 = 0.25 mg/kg); inhibits the contractile response to norepinephrine in isolated rabbit aorta (Kb = 11 nM); decreases systolic blood pressure and heart rate in rat models of hypertension from 3-30 mg/kg; inhibits SARS-CoV-2 Mpro (IC50 = 204.6 µg/ml) and reduces viral infectivity in SARS-CoV-2-infected Vero E6 cells (IC50 = 0.350 µg/ml) |
| Size | 100 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | BM 14190 |
| Gene, Accession, CAS # | CAS: 72956-09-3 |
| Catalog # | 15418-100 |
| Price | $57.00 |
| Order / More Info | Carvedilol from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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