Zofenoprilat from CAYMAN CHEMICAL COMPANY
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| Product Name | Zofenoprilat |
| Description | An ACE inhibitor (IC50 = 8 nM for the rabbit lung enzyme) and active metabolite of zofenopril; inhibits angiotensin I- or bradykinin-induced contractions of isolated guinea pig ileum (EC50s = 3 and 1 nM, respectively); decreases basal endothelin-1 secretion and NO production, as well as prevents TNF-α-induced increases in ROS and decreases GSH levels, in HUVECs at 10 nM; protects primary human cardiac microvascular endothelial cells against doxorubicin-induced cytotoxicity at 10 µM; increases H2S production in, and adhesion, migration, and proliferation of, HUVECs at 10 µM; reduces end diastolic pressure and LDH release in a Langendorff isolated perfused rat heart model of ischemia-reperfusion injury at 400 µM |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | SQ 26,333|Zofenopril-SH |
| Gene, Accession, CAS # | CAS: 75176-37-3 |
| Catalog # | 38124-5 |
| Price | $758.00 |
| Order / More Info | Zofenoprilat from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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