PAD4 Inhibitor Screening Assay Kit (AMC) from CAYMAN CHEMICAL COMPANY
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| Product Name | PAD4 Inhibitor Screening Assay Kit (AMC) |
| Description | Cayman's PAD4 Inhibitor Screening Assay Kit (AMC) provides a convenient method for screening human PAD4 inhibitors. This assay utilizes a fluorescent substrate (Z-Arg-AMC) consisting of an arginine residue, a carboxybenzyl group, and a fluorophore (7-amino-4-methylcoumarin, AMC).7 Acylation of AMC onto the arginine residue masks the fluorescence of the fluorophore. In the absence of PAD4, the substrate remains unaltered, allowing the developer to release free AMC. In the presence of PAD4, the arginine of the substrate is citrullinated, and while the reaction is quenched by the addition of developer, free AMC is not released. Fluorescence is analyzed with an excitation wavelength of 355-365 nm and an emission wavelength of 445-455 nm. The fluorescent signal is inversely proportional to the amount of citrullination by PAD4. |
| Size | 96 Well |
| Concentration | n/a |
| Applications | Fluorescence, High-Throughput Screening |
| Other Names | PADI4|PADI5|PDI5|Peptidylarginine Deiminase 4|Protein Arginine Deiminase 4 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 701320-96WELLS |
| Price | $493.00 |
| Order / More Info | PAD4 Inhibitor Screening Assay Kit (AMC) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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