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Product Name | IPA-3 |
Description | An inhibitor of PAK1 activation (IC50 = 2.5 µM); does not inhibit pre-activated PAK1; selectively inhibits PAK1, PAK2, and PAK3 activation over PAK4, PAK5, and PAK6 activation at 10 µM; inhibits SARS-CoV-2 nsp15 in a FRET assay (IC50 = 6.8 µM); inhibits SARS-CoV-2 replication in infected Vero CCL-81 cells (IC50 = 8.5 µM); inhibits the proliferation of H2M and MHCC97-L cells at 5 and 10 µM; reduces tumor growth in an MHCC97-L cell mouse xenograft model at 2 and 4 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Inhibitor of PAK1 Activation 3 |
Gene, Accession, CAS # | CAS: 42521-82-4 |
Catalog # | 14759-5 |
Price | $57.00 |
Order / More Info | IPA-3 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |