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Product Name | Lamevudine |
Description | An antiviral; selectively inhibits wild-type HCV NS5BΔ55 over NS5BΔ55S282T (IC50s = 0.07 and 25 µM, respectively); selectively inhibits replication of HCV replicons in wild-type HBI10A cells over HBI10A cells containing NS5BΔ55S282T (EC50s = 0.3 and 10.1 µM, respectively); reduces the cytopathic effect of positive-strand RNA viruses in the families Flaviviridae (EC50s = 0.3-15 µM) and Picornaviridae (EC50s = 0.5-5.9 µM) but not viruses of the negative-strand RNA virus family Paramyxoviridae; inhibits the cytopathic effect and reduces virus yields of the Zika virus strain MR766 in infected Vero cells (EC50s = 20 and 9.6 µM, respectively); reduces serum viral load and delays virus-induced morbidity and mortality in Zika virus-infected AG129 mice at 50 mg/kg per day |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 7-Deaza-2?-C-methyladenosine|MK-0608 |
Gene, Accession, CAS # | CAS: 443642-29-3 |
Catalog # | 39925-25 |
Price | $340.00 |
Order / More Info | Lamevudine from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |