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Product Name | YM-155 (chloride) |
Description | A survivin inhibitor; inhibits survivin promoter activity in a reporter assay (IC50 = 0.54 nM); reduces survivin levels and induces apoptosis in PC3 and PPC-1 prostate cancer cells from 10-1,000 nM; inhibits tumor growth, decreases intratumor survivin levels, and induces tumor regression in a PC3 mouse xenograft model at 3 and 10 mg/kg; inhibits SARS-CoV-2 PLpro (IC50 = 2.47 µM) and reduces the number of viral RNA copies in SARS-CoV-2-infected Vero E6 cells |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 753440-91-4 YM155 PC 3 PPC1 MiaPaCa2 SARSCoV2 SARS Cov2 corona virus E 6 |
Gene, Accession, CAS # | CAS: 355406-09-6 |
Catalog # | 36827-25 |
Price | $176.00 |
Order / More Info | YM-155 (chloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |