Acetylshikonin from CAYMAN CHEMICAL COMPANY

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Product NameAcetylshikonin
DescriptionA naphthoquinone that has diverse biological activities; inhibits a panel of 10 CYPs (IC50s = 1.4-4.0 µM); cytotoxic to H1975, A549, PC-9, and H460 NSCLC cells (IC50s = 3.9, 4.7, 20.7, and 17.3 µM, respectively); inhibits the migration of, as well as reduces EGFR and STAT3 signaling and induces apoptosis in, H1975, PC-9, and H460 cells at 0.5, 1, and 2 µM; reduces tumor weight and intratumoral STAT3 phosphorylation in an H1975 mouse xenograft model at 1 mg/kg; inhibits SARS-CoV-2 PLpro (IC50 = 5.05 µM); reduces BALF levels of Tnf-α, Il-1α, and Il-6 in a mouse model of acute lung injury induced by poly (I:C) and SARS-CoV-2 spike glycoprotein at 300 mg/kg
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesNSC 110199
Gene, Accession, CAS #CAS: 24502-78-1
Catalog #40144-10
Price$358.00
Order / More InfoAcetylshikonin from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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