SET8 Methyltransferase Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY
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| Product Name | SET8 Methyltransferase Inhibitor Screening Assay Kit |
| Description | SET Domain-containing Protein 8 is a MT that selectively mono-methylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. Cayman's SET8 MT Inhibitor Screening Assay provides a convenient method for screening human SET8 inhibitors. The transfer of the methyl group from SAM by SET8 (provided in the kit) to the acceptor peptide (H4K20) generates S-adenosylhomocysteine, which is rapidly converted to urate and H2O2 using an enzyme mixture provided in the kit. The H2O2 formed reacts with ADHP (10-acetyl-3,7-dihydroxyphenoxazine) to produce the highly fluorescent compound resorufin (excitation 530-540 nm; emission 585-595 nm). |
| Size | 96 Well |
| Concentration | n/a |
| Applications | n/a |
| Other Names | PR-Set7|SET domain-containing (lysine methyltransferase) 8|SETD8 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 700350-96WELLS |
| Price | $689.00 |
| Order / More Info | SET8 Methyltransferase Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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