A-804598 from CAYMAN CHEMICAL COMPANY
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| Product Name | A-804598 |
| Description | A potent and selective competitive antagonist of the P2X7 receptor (IC50s = 9.9 and 10.9 nM in 132N1 cells transfected with the rat or mouse receptor, respectively), inhibits IL-1β release in LPS and IFN-γ-stimulated THP-1 cells (IC50 = 8.5 nM); selective over other P2X and P2Y receptors at concentrations up to 100 µM; prevents footshock-induced increases in IL-1β mRNA in the rat hypothalamus , |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | P2X-7 A804598 IL1β IL1b P2-X Y THP1 IFNγ lipopolysaccharide IFNg GPCR interleukin |
| Gene, Accession, CAS # | CAS: 1125758-85-1 |
| Catalog # | 20060-5 |
| Price | $93.00 |
| Order / More Info | A-804598 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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