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Product Name | Carboxyamidotriazole |
Description | An orally bioavailable, non-selective calcium channel blocker; blocks L- and T-type calcium channels in GH3 rat pituitary cancer cells (IC50s = 0.5 and 1.5 µg/ml, respectively); blocks carbachol- and A23187-stimulated calcium influx in CHO cells expressing human recombinant M5 receptors (IC50s = 935 and 359 nM, respectively); inhibits the growth of T. gondii in non-cancerous human fibroblasts and HeLa human cervical cancer cells (IC50 = 0.06 µg/ml for both); inhibits the growth of human FaDu and EVSCC17M squamous cell carcinoma cells (IC50s = 13 and 15 µM, respectively) and of HUVECs (IC50 = 1 µM); inhibits angiogenesis in a chicken chorioallantoic membrane assay in vivo at 20 µM |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | CAI|L-651,582|NSC 609974 |
Gene, Accession, CAS # | CAS: 99519-84-3 |
Catalog # | 28732-25 |
Price | $414.00 |
Order / More Info | Carboxyamidotriazole from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |