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Product Name | diABZI STING Agonist-1 (hydrochloride) |
Description | An agonist of the STING pathway; induces secretion of IFN-β in human PBMCs (EC50 = 130 nM); increases serum levels of IFN-β, IL-6, TNF, and KC/GROα in wild-type mice at 2.5 mg/kg; inhibits the cytopathic effect of HCoV-229E in infected MRC-5 cells (EC50 = 3 nM); decreases the level of SARS-CoV-2 RNA in primary human bronchial airway epithelial cells in an air-liquid interface assay; decreases tumor volume and increases survival in a CT26 murine colorectal cancer model at 3 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | diABZI Stimulator of Interferon Genes Agonist 1|Diamidobenzimidazole Stimulator of Interferon Genes Agonist 1|Diamidobenzimidazole STING Agonist 1|Stimulator of Interferon Genes Agonist (Compound 3)|STING Agonist (Compound 3) |
Gene, Accession, CAS # | CAS: 2138299-34-8 |
Catalog # | 28054-1 |
Price | $299.00 |
Order / More Info | diABZI STING Agonist-1 (hydrochloride) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |