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Product Name | SJB2-043 |
Description | An inhibitor of the USP1-UAF complex (IC50 = 0.544 µM for its deubiquitinase activity) and SARS-CoV-2 PLpro (IC50s = 0.56 and 0.091 µM using Z-LRGG-AMC or Ub-AMC, respectively, as PLpro substrates); reduces the levels of USP1, ID-1, ID-2, and ID-3 in K562 cells at 0.5-10 µM; decreases the viability of K562 cells (EC50 = 1.07 µM); induces apoptosis in K562 cells in a concentration-dependent manner |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | SJB2043 SJB 2-043 2043 USP UAF SARSCoV SARSCoV2 corona-virus PL-pro ID1 ID2 ID3 K-562 MG-132 ZLRGGAMC ZLRGG amino methylcoumarin methyl-coumarin UbAMC |
Gene, Accession, CAS # | CAS: 63388-44-3 |
Catalog # | 36605-10 |
Price | $112.00 |
Order / More Info | SJB2-043 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |