Sphingosine Kinase 2 Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY
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| Product Name | Sphingosine Kinase 2 Inhibitor Screening Assay Kit |
| Description | Cayman's SPHK2 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human SPHK2, an enzyme with roles in cell proliferation, apoptosis, and epigenetic regulation of gene expression. The assay uses an SPHK-specific fluorogenic substrate, NBD-sphingosine. SPHK2 phosphorylates this substrate generating a shift in its spectral properties, which can be easily quantified using a fluorescence plate reader at excitation and emission wavelengths of 550 and 584 nm, respectively. The reversible dual SPHK1/2 inhibitor SLC5111312 is included as a positive control and inhibits SPHK2 with an IC50 value of approximately 4 µM. |
| Size | 96 Well |
| Concentration | n/a |
| Applications | Fluorescence |
| Other Names | SK2|SPHK2 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 701870-96WELLS |
| Price | $458.00 |
| Order / More Info | Sphingosine Kinase 2 Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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