Mebhydroline (1,5-naphthalenedisulfonate) from CAYMAN CHEMICAL COMPANY

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Product NameMebhydroline (1,5-naphthalenedisulfonate)
DescriptionA histamine H1 receptor antagonist (Ki = 7.6 nM); selective for the histamine H1 receptor over muscarinic acetylcholine receptors (mAChRs; Ki = 180 nM); inhibits acid sphingomyelinase in H4 neuroglioma cells at 10 µM; binds to the FXR ligand-binding domain (Kd = 9.87 µM); inhibits GW 4064-induced transactivation of FXR in HEK293T cells expressing the human receptor; binds to Zika virus RdRp (Kd = 22.62 µM) and reduces viral replication in Zika-infected Vero cells (EC50 = 5.14 µM); decreases blood glucose and plasma HbA1c levels in db/db diabetic mice at 30 mg/kg
Size5 g
Concentrationn/a
Applicationsn/a
Other NamesMebhydrolin napadisylate
Gene, Accession, CAS #CAS: 6153-33-9
Catalog #40281-5
Price$100.00
Order / More InfoMebhydroline (1,5-naphthalenedisulfonate) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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