Emetine (hydrochloride hydrate) from CAYMAN CHEMICAL COMPANY

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Product NameEmetine (hydrochloride hydrate)
DescriptionAn alkaloid with diverse biological activities; active against several strains of E. histolytica amoebae (IC50s = 0.73-10.22 µg/ml); inhibits NF-κB signaling induced by TNF-α or IL-1β (IC50s = 2 and 4.2 µM, respectively, in a cell-based β-lactamase reporter assay); increases caspase-3/7 activity in ME180 cells (EC50 = 1.1 µM); cytotoxic to HeLa cells; reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s = 0.46 and 0.5 µM, respectively); induces emesis in ferrets at 5 mg/kg, an effect that can be prevented by ondansetron
Size100 mg
Concentrationn/a
Applicationsn/a
Other Names483-18-1 316-42-7 NSC 33669 NSC33669 Cephaeline Emetin Entamoeba NFκB TNFα IL1β ME-180 HT-3 5HT 5HT3 anti-viral SARS-CoV-2 SARSCoV2 covid-19 covid19 coronavirus corona virus
Gene, Accession, CAS #CAS: 7083-71-8
Catalog #21048-100
Price$438.00
Order / More InfoEmetine (hydrochloride hydrate) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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