A-784168 from CAYMAN CHEMICAL COMPANY
Search, find, compare suppliers for A-784168 products.
| Edit | |
|---|---|
| Product Name | A-784168 |
| Description | A TRPV1 competitive antagonist; inhibits capsaicin-induced activation of TRPV1 in 1321N1 cells expressing TRPV1 (IC50 = 25 nM for the human receptor); selective for TRPV1 over a panel of 74 neurotransmitter receptors, ion channels, and other TRP channels at 50 µM but does act as an antagonist at TRPM8 (IC50 = 20.8 µM); inhibits TRPV1 activation induced by mildly acidic conditions, NADA, or anandamide in HEK293 cells (IC50s = 14, 33.7, and 35.1 nM, respectively); inhibits capsaicin-induced currents in primary rat dorsal root ganglion neurons (IC50 = 10 nM); inhibits NGF-induced thermal hypersensitivity and mechanical hypersensitivity in rats at 200 µmol/kg |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | A784168 TRPV 1 TRPM 8 HEK 293 |
| Gene, Accession, CAS # | CAS: 824982-41-4 |
| Catalog # | 32855-10 |
| Price | $257.00 |
| Order / More Info | A-784168 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY
Return to Products