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Product Name | Chloroquine (phosphate) |
Description | An aminoquinoline; an inhibitor of autophagy with antimalarial, anti-inflammatory, anticancer, and antiviral activities; inhibits autophagosome-lysosome fusion in HeLa cells at 100 µM; active against the chloroquine-sensitive GC03 strain of P. falciparum (IC50 = 29.2 nM); prevents SARS-CoV-2 infection in Vero cells (EC50 = 1.13 µM) but does not inhibit SARS-CoV replication in the lungs in a mouse model of SARS-CoV infection; inhibits the growth of human SSC25 and CAL 27 oral squamous cell carcinoma cells (IC50s = 29.9 and 17.3 µM, respectively), as well as A498, SN12C, RXF393, and 769-P renal cancer cells (IC50s = 16, 62, 81, and 25 µM, respectively); reduces tumor growth in a CAL 27 mouse xenograft model and a 4T1 mouse allograft model at 50 mg/kg |
Size | 50 g |
Concentration | n/a |
Applications | n/a |
Other Names | DL-Chloroquine|NSC 14050 |
Gene, Accession, CAS # | CAS: 50-63-5 |
Catalog # | 14194-50 |
Price | $115.00 |
Order / More Info | Chloroquine (phosphate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |