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Product Name | Carvedilol |
Description | A β-adrenergic receptor antagonist (Kds = 1.78, 0.4, and 5.01 nM for β1-, β2-, and β3-ARs, respectively); selectively binds to α1- over α2-ARs (Kis = 0.81 and 3,400 nM, respectively); reverses increases in heart rate induced by isoproterenol in isolated guinea pig atria (Kb = 0.8 nM); prevents epinephrine-induced premature ventricular beats in a rat model of arrhythmia (ED50 = 0.25 mg/kg); inhibits the contractile response to norepinephrine in isolated rabbit aorta (Kb = 11 nM); decreases systolic blood pressure and heart rate in rat models of hypertension from 3-30 mg/kg; inhibits SARS-CoV-2 Mpro (IC50 = 204.6 µg/ml) and reduces viral infectivity in SARS-CoV-2-infected Vero E6 cells (IC50 = 0.350 µg/ml) |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | BM 14190 |
Gene, Accession, CAS # | CAS: 72956-09-3 |
Catalog # | 15418-50 |
Price | $32.00 |
Order / More Info | Carvedilol from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |