ATN-161 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY

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Product NameATN-161 (trifluoroacetate salt)
DescriptionAn integrin receptor antagonist; binds to αVβ3 and αVβ5 receptors (Kds = 0.69 and 1 µM, respectively) in MDA-MB-231 cells; inhibits the interaction between αVβ5 and human ACE2 or SARS-CoV-2 spike protein in cell-free assays; reduces viral titers in Vero E6 cells infected with SARS-CoV-2 (EC50 = 3.16 µM); inhibits VEGF-induced migration and capillary tube formation of primary human choroidal endothelial cells at 0.1 µM; reduces tumor growth and metastasis in an MDA-MB-231 mouse xenograft model at 1 mg/kg; reduces infarct volume and edema in a mouse model of MCAO-induced ischemic stroke at 1 mg/kg
Size1 mg
Concentrationn/a
Applicationsn/a
Other NamesAc-PHSCN-NH2|PHSCN Peptide
Gene, Accession, CAS #CAS: 904763-27-5
Catalog #34056-1
Price$32.00
Order / More InfoATN-161 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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