Edit |   |
---|---|
Product Name | ATN-161 (trifluoroacetate salt) |
Description | An integrin receptor antagonist; binds to αVβ3 and αVβ5 receptors (Kds = 0.69 and 1 µM, respectively) in MDA-MB-231 cells; inhibits the interaction between αVβ5 and human ACE2 or SARS-CoV-2 spike protein in cell-free assays; reduces viral titers in Vero E6 cells infected with SARS-CoV-2 (EC50 = 3.16 µM); inhibits VEGF-induced migration and capillary tube formation of primary human choroidal endothelial cells at 0.1 µM; reduces tumor growth and metastasis in an MDA-MB-231 mouse xenograft model at 1 mg/kg; reduces infarct volume and edema in a mouse model of MCAO-induced ischemic stroke at 1 mg/kg |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | Ac-PHSCN-NH2|PHSCN Peptide |
Gene, Accession, CAS # | CAS: 904763-27-5 |
Catalog # | 34056-1 |
Price | $32.00 |
Order / More Info | ATN-161 (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |