SET7/9 Methyltransferase Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY
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| Product Name | SET7/9 Methyltransferase Inhibitor Screening Assay Kit |
| Description | SET7/9 is an MT that acts on various substrates including histone 3 at lysine residue 4 (H3K4), p53, and the transcription factor TAF 10. Unlike most SET proteins, SET7/9 is exclusively a mono-methylase. Cayman's SET7/9 MT Inhibitor Screening Assay provides a convenient method for screening SET7/9 inhibitors. The transfer of the methyl group from SAM by SET7/9 to the acceptor peptide (TAF 10) generates SAH, which is rapidly converted to urate and H2O2 using an enzyme mixture provided in the kit. A subsequent reaction between H2O2 and ADHP (10-acetyl-3,7-dihydroxyphenoxazine) produces the highly fluorescent compound resorufin. Resorufin fluorescence is analyzed using an excitation wavelength between 530-540 nm and an emission wavelength between 585-595 nm. |
| Size | 96 Well |
| Concentration | n/a |
| Applications | Fluorescence |
| Other Names | KMT7|SET Domain-containing Protein 7/9|SETD7/9 |
| Gene, Accession, CAS # | n/a |
| Catalog # | 700270-96WELLS |
| Price | $689.00 |
| Order / More Info | SET7/9 Methyltransferase Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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