VIP (human, porcine, rat, ovine) (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY
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| Product Name | VIP (human, porcine, rat, ovine) (trifluoroacetate salt) |
| Description | A 28-amino acid peptide that has roles as a hormone and neurotransmitter and has diverse biological activities; a VPAC1 and VPAC2 agonist (EC50s = 3 and 8 nM, respectively, in CHO cell membranes expressing the recombinant human receptors); selective for these receptors over PAC1 (Ki = 500-1,000 nM in radioligand binding assays); induces relaxation of carbachol-precontracted isolated human fundus or antrum circular smooth muscle strips from 10-300 nM; reduces pentagastrin-induced increases in gastric acid secretion and mucosal blood flow in conscious dogs at 8 µg/kg; decreases serum and peritoneal lavage levels of TNF-α and IL-6 and reduces mortality in a mouse model of LPS-induced endotoxemia from 5-10 nM; inhibits SARS-CoV-2 replication in Calu-3 human lung epithelial cells and isolated human peripheral blood monocytes at 5 nM; inhibits production of IL-6, IL-8, and TNF-α in SARS-CoV-2-infected Calcu-3 cells |
| Size | 500 µg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Vasoactive Intestinal Peptide |
| Gene, Accession, CAS # | n/a |
| Catalog # | 24996-500 |
| Price | $116.00 |
| Order / More Info | VIP (human, porcine, rat, ovine) (trifluoroacetate salt) from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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