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Product Name | MS023 |
Description | An inhibitor of type I PRMTs (IC50s = 30, 119, 83, 4, and 5 nM for PRMT1, -3, -4, -6, and -8, respectively); selective for these type I PRMTs over PRMT5, -7, and -9, as well as a panel of 25 PKMTs and DNMTs at 10 µM; inhibits methylation of H4R3 in MCF-7 cells and H3R2 in HEK293 cells (IC50s = 9 and 56 nM, respectively); inhibits methylation of the SARS-CoV-2 nucleocapsid protein and the replication of SARS-CoV-2 in Vero E6 cells at 20 µM; reduces tumor growth in a Huh7 mouse xenograft model at 160 mg/kg |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | MS 023 SARSCoV2 COVID-19 COVID19 |
Gene, Accession, CAS # | CAS: 1831110-54-3 |
Catalog # | 34786-10 |
Price | $174.00 |
Order / More Info | MS023 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |