ABBV-744 from CAYMAN CHEMICAL COMPANY
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| Product Name | ABBV-744 |
| Description | A BD2 bromodomain inhibitor (Kis = 4.6, 4.9, 1.6, and 1 nM for BRD2, -3, -4, and -T, respectively); selective for BD2 over BD1 bromodomains in a TR-FRET assay (Kis = 1,162, 3,140, 521, and 917 nM for BRD2, -3, -4, and -T, respectively); inhibits proliferation of SKM-1 leukemia cells (IC50 = 6.7 nM); induces cell cycle arrest at the G1 phase in LNCaP cells; reduces tumor volume in a SKM-1 mouse xenograft model at 18.8 mg/kg; reduces tumor growth in LNCaP and MDA PCa 2b mouse xenograft models at 1 and 4.7 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ABBV744 BD BRD 1 2 3 4 T TRFRET SKM1 G 1 LN CaP |
| Gene, Accession, CAS # | CAS: 2138861-99-9 |
| Catalog # | 30470-5 |
| Price | $68.00 |
| Order / More Info | ABBV-744 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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