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Product Name | sPLA2 (Type X) Inhibitor Screening Assay Kit |
Description | Cayman's sPLA2 (Type X) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human sPLA2 (Type X), a phospholipase that hydrolyzes PE and PC at the sn-2 position. The assay uses a sulfur-containing analog of 1,2-diheptanoyl-sn-glycero-3-PC (di-C7-PC) as a substrate. Upon hydrolysis by sPLA2 (Type X) at the sn-2 position, free thiols can be detected by the sPLA2 Assay Probe resulting in a product that can be easily quantified using its absorbance at a wavelength of 410 nm. The potent and reversible sPLA2 (Type X) inhibitor, sPLA2 Control Inhibitor, also known as LY315920 or varespladib, is included as a positive control and inhibits the enzyme with an IC50 value of approximately 11 nM. |
Size | 384 Well |
Concentration | n/a |
Applications | n/a |
Other Names | GXsPLA2|Phosphatidylcholine 2-Acylhydrolase 10|PLA2G10|Secretory Phospholipase A2 (Group 10)|Secretory Phospholipase A2 (Group X)|Secretory Phospholipase A2 (mouse Group X)|Secretory Phospholipase A2 (Type X)|sPLA2-X |
Gene, Accession, CAS # | n/a |
Catalog # | 702480-384WELLS |
Price | $547.00 |
Order / More Info | sPLA2 (Type X) Inhibitor Screening Assay Kit from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |