Thiorphan from CAYMAN CHEMICAL COMPANY
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| Product Name | Thiorphan |
| Description | A NEP inhibitor (IC50 = 0.007 µM); inhibits NEP over NEP2 (IC50 = 22 µM) and ACE and ECE1 (Kis = >100 and >10,000 nM, respectively, in cell-free assays); increases bradykinin-induced relaxation of isolated porcine coronary artery rings precontracted with potassium chloride under hypoxic, but not normoxic, conditions at 10 µM; reduces pentagastrin-induced increases in gastric acid output by 64% in rats at 50 µg i.c.v., but not 1.7 and 17 mg/kg i.v.; increases cortical levels of insoluble Aβ40 and decreases time spent in the platform quadrant in the Morris water maze, indicating impaired reference memory, in rats at 2 mg/ml i.c.v. |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | DL-Thiorphan |
| Gene, Accession, CAS # | CAS: 76721-89-6 |
| Catalog # | 15600-10 |
| Price | $115.00 |
| Order / More Info | Thiorphan from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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