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Product Name | GS-441524 |
Description | An antiviral nucleoside analog; metabolized to an active triphosphate form that induces RNA chain termination and inhibits viral polymerases; active against MERS-CoV and SARS-CoV in infected primary HAE cells (EC50s = 0.86 and 0.18 µM, respectively); reduces viral plaque formation in SARS-CoV-2-infected Vero E6 and Calu-3 2B4 cells (EC50s = 0.42 and 0.62 mM, respectively); cytoprotective against HCV, YFV, DENV-2, influenza A, and parainfluenza 3 in cell-based assays (EC50s = 4.1, 11, 9.46, 27.9, and 1.71 µM, respectively) |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | GS441524 anti-viral MERSCoV SARSCoV DENV2 para-influenza SARS-CoV-2 SARSCoV2 covid-19 covid19 coronavirus corona virus |
Gene, Accession, CAS # | CAS: 1191237-69-0 |
Catalog # | 30469-10 |
Price | $77.00 |
Order / More Info | GS-441524 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |