Thapsigargin from CAYMAN CHEMICAL COMPANY
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| Product Name | Thapsigargin |
| Description | A SERCA inhibitor (IC50 = ~30 nM for the rat liver microsomal enzyme) and ER stress inducer; increases intracellular calcium levels in isolated rat hepatocytes (EC50 = ~80 nM) and protein levels of DDIT3, GRP78, as well as phosphorylation of PERK and eIF2α in SH-SY5Y cells at 1 µM; protects primary mouse BMDMs against TNF- and zVAD-induced necroptosis at 2 µg/ml for 1 h; induces apoptosis in SW-13 cells from 2-16 µM; induces autophagosome accumulation in MEFs at 3 µM; reduces viral titers in Vero E6 cells co-infected with SARS-CoV-2 and influenza A strain H1N1 at 0.5 µM; reduces tumor volume in an SW-13 mouse xenograft model 1 mg/kg |
| Size | 5 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | calcium CA DDIT GRP eIF SHSY5Y SW13 coinfected corona-virus CoV2 SARSCoV SARSCoV2 flu |
| Gene, Accession, CAS # | CAS: 67526-95-8 |
| Catalog # | 10522-5 |
| Price | $274.00 |
| Order / More Info | Thapsigargin from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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