A-867744 from CAYMAN CHEMICAL COMPANY

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Product NameA-867744
DescriptionA positive allosteric modulator of α7 nAChRs; selective for α7 nAChRs over α3β2- and α4β2 subunit-containing nAChRs (IC50s = 0.023, 19.5 and 6.4 µM, respectively) and 5-HT3A receptors (Ki = >30 µM); potentiates ACh-induced currents in Xenopus oocytes expressing human α7 nAChRs (EC50 = ~1 µM); improves sensory gating deficits in a paired auditory stimulus paradigm in mice from 0.1-10 µmol/kg, i.p.
Size100 mg
Concentrationn/a
Applicationsn/a
Other NamesA867744 α-7 α3-β2 α3β-2 3β2 4β2 5HT
Gene, Accession, CAS #CAS: 1000279-69-5
Catalog #32974-100
Price$783.00
Order / More InfoA-867744 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
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http://www.caymanchem.com

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