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Product Name | A-867744 |
Description | A positive allosteric modulator of α7 nAChRs; selective for α7 nAChRs over α3β2- and α4β2 subunit-containing nAChRs (IC50s = 0.023, 19.5 and 6.4 µM, respectively) and 5-HT3A receptors (Ki = >30 µM); potentiates ACh-induced currents in Xenopus oocytes expressing human α7 nAChRs (EC50 = ~1 µM); improves sensory gating deficits in a paired auditory stimulus paradigm in mice from 0.1-10 µmol/kg, i.p. |
Size | 100 mg |
Concentration | n/a |
Applications | n/a |
Other Names | A867744 α-7 α3-β2 α3β-2 3β2 4β2 5HT |
Gene, Accession, CAS # | CAS: 1000279-69-5 |
Catalog # | 32974-100 |
Price | $783.00 |
Order / More Info | A-867744 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |