25-hydroxy Cholesterol from CAYMAN CHEMICAL COMPANY
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| Product Name | 25-hydroxy Cholesterol |
| Description | An oxysterol; suppresses endogenous cholesterol synthesis by preventing SREBP transport to the Golgi; inhibits IgA class switching induced by LPS and various cytokines in B cells (IC50 = ~50 nM); inhibits replication of SARS-CoV-2 in Vero cells (EC50 = 3.675 µM); reduces viral RNA loads in the lung and trachea in a mouse model of SARS-CoV-2 infection at 100 mg/kg per day; serum levels are increased in hACE2 mice in a model of SARS-CoV-2 infection and in a patient with COVID-19 |
| Size | 100 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 16505-96-7 anti-viral SARS-CoV-2 SARSCoV2 covid-19 covid19 coronavirus corona virus hydroxycholesterol 25-HC 25HC |
| Gene, Accession, CAS # | CAS: 2140-46-7 |
| Catalog # | 11097-100 |
| Price | $326.00 |
| Order / More Info | 25-hydroxy Cholesterol from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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