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Product Name | Bisoprolol (hemifumarate) |
Description | A β1-AR antagonist (Ki = 25 nM for the human receptor); selective for β1- over β2-ARs (Ki = 480 nM for the human receptor in a radioligand binding assay); binds to rat ventricular myocytes and heart membranes that endogenously express β1-ARs and β1- and β2-ARs, respectively (Kis = 20 and 38.1 nM, respectively); inhibits isoproterenol-induced increases in heart rate and myocardial contractility in conscious dogs at 0.3 mg/kg; decreases blood pressure and heart rate in SHRs at 7.5 mg/kg twice per day over 19 weeks; inhibits SARS-CoV-2 Mpro (IC50 = 118.5 µg/ml) and reduces viral infectivity in SARS-CoV-2 infected Vero E6 cells (IC50 = 15.917 µg/ml) |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | EMD 33512 |
Gene, Accession, CAS # | CAS: 104344-23-2 |
Catalog # | 23827-50 |
Price | $32.00 |
Order / More Info | Bisoprolol (hemifumarate) from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |